Journal Articles

    A. Das, M. Haque, M. Chikhani, O. Cole, W. Wang, J.G. Hardman and D.G. Bates, "Hemodynamic effects of lung recruitment maneuvers in acute respiratory distress syndrome", BMC Pulmonary Medicine, 17:34, 2017

    M. Chikhani, A. Das, M. Haque, W. Wang, D.G. Bates, and J.G. Hardman, "High PEEP in ARDS: evaluating the trade-off between improved oxygenation and decreased oxygen delivery", British Journal of Anaesthesia, 117(5): 650–8, 2016

    W. Wang, A. Das, O. Cole, M. Chikhani, J.G. Hardman and D.G. Bates, Computational simulation indicates that moderately high frequency ventilation can allow safe reduction of tidal volumes and airway pressures in ARDS patients, Intensive Care Medicine Experimental, 3(33), 2015

    A. Das, O. Cole, M. Chikhani, W. Wang, T. Ali, M. Haque, J.G. Hardman and D.G. Bates, Evaluation of lung recruitment maneuvers in acute respiratory distress syndrome using computer simulation, Critical Care, 19(8), 2015

    W. Wang, A. Das, T. Ali, O. Cole, M. Chikhani, M. Haque, J.G. Hardman and D.G. Bates, Can computer simulators accurately represent the pathophysiology of individual COPD patients?, Intensive Care Medicine Experimental, 2(23), 2014

    A.Das, P.P. Menon, J. Hardman and D.G. Bates, Optimization of Ventilation Settings for Pulmonary Disease States, IEEE Transactions on Biomedical Engineering, 60(6):1599-1607, 2013

    A. Das, Z. Gao, P.P. Menon, J. Hardman and D.G. Bates, A Systems Engineering approach to validation of a pulmonary physiology simulator for clinical applications, Journal of The Royal Society Interface, 8(54):44-55, 2011

    P. Sinha, K. Corrie, A. Bersten, J.G. Hardman, N. Soni, Ventilatory ratio: validation in an ex vivo model and analysis in ARDS/ALI patients. Critical Care, 15:1-190, 2011


Conference Presentations

    M. Laviola, A. Das, M. Chikhani, D.G. Bates and J.G. Hardman "Investigating the effect of cardiac oscillations and deadspace gas mixing during apnea using computational simulation", to appear in proceedings of the 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, JeJu Island, S. Korea, 2017.

    S. Saffaran, A. Das, J.G. Hardman, N. Yehya, and D.G. Bates, "Development and Validation of a Computational Simulator for Pediatric ARDS Patients", to appear in proceedings of the 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, JeJu Island, S. Korea, 2017

    A. Das, M. Haque, M. Chikhani, W. Wang, J.G. Hardman and D.G. Bates, "Creating Virtual ARDS Patients", in proceedings of the 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Orlando, 2016

    A. Das, M. Haque, M. Chikhani, W. Wang, T. Ali, O. Cole, J.G. Hardman and D.G. Bates, Development of an Integrated Model of Cardiovascular and Pulmonary Physiology for the Evaluation of Mechanical Ventilation Strategies, in Proceedings of the 37th IEEE Engineering in Medicine and Biology Conference, Milano, 2015

    A. Das, W. Wang, T. Ali, O. Cole, M. Chikhani, M. Haque, J.G. Hardman and D.G. Bates, Development of Personalised Treatment Strategies in Respiratory Medicine via Computational Simulation of Individual Patients, in Proceedings of the IEEE Engineering in Medicine and Biology Conference, Mini-Symposium on Advanced Engineering Methods in Respiratory Medicine, Chicago, 2014

    Ali, T., Das, A., Chikhani, M., Haque, M., Cole, O., Wang, W., Bates, DG., and Hardman, JG., Mathematical simulation of the human systemic and pulmonary circulation to investigate mechanical ventilation strategies, Physiology Society Main Meeting London, UK 29th JUNE-2nd JULY 2014

    T. Ali, A. Cole, A. Das, M. Chikhani, M. Haque, W. Wang, J.G. Hardman, and D.G Bates. Using a novel mathematical model of the cardiopulmonary system to investigate the effects of mechanical ventilation and oxygen delivery, Fifth edition of a series devoted to Mathematical and Numerical Modelling of Physiological Flows (MPF) 2013- Invited talk

    A. Das, A. Cole, T. Ali, M. Chikhani, M. Haque, W. Wang, J.G. Hardman, and D.G. Bates . Using modelling to investigate mechanical ventlation strategies in acute respiratory distress syndrom, 26th European Society of Intensive Care Medicine (ESICM) ANNUAL CONGRESS PARIS, FRANCE, OCTOBER 2013